I just posted on my Mayo's Mind blog about how I believe that malfunctioning feedback controls not only cause someone to be overweight, but also cause their brain to actively defend this abnormally heavy bodyweight, producing the familiar yo-yo like effect on bodyweight if they try to consciously restrict their calories (either through eating fewer calories, trying to "burn" off extra stored calories, or both). This could prevent someone from losing weight even if they are technically starving themselves. Check it out!
Bryan
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